Apr 18, 2025
The FAME 3 trial 5-year results, TAVR at 5 years, pacers after
TAVR, and mavacamten not a wonder drug are the topics John
Mandrola, MD, discusses in this week’s podcast.
This podcast is intended for healthcare professionals
only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I FAME 3 at Five Years
Stents as Good as Surgery for Triple-Vessel Disease
https://www.medscape.com/viewarticle/noninvasive-stents-good-surgery-triple-vessel-disease-2025a10007l4
- Main trial NEJM
https://www.nejm.org/doi/full/10.1056/NEJMoa2112299
- Circulation 3-years
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.065770
- 5-year results Lancet
10.1016/S0140-6736(25)00505-7 https://linkinghub.elsevier.com/retrieve/pii/S0140673625005057
II TAVR in Low-Risk Patients at 5 years
5-Year TAVR, Surgery Outcomes Similar in Low-Risk
Patients
https://www.medscape.com/viewarticle/5-year-tavr-surgery-outcomes-similar-low-risk-patients-2025a10007zl
- EVOLUT Low-Risk 5 years
https://www.jacc.org/doi/10.1016/j.jacc.2025.03.004
- EVOLUT Editorial – We're Halfway There
https://www.jacc.org/doi/10.1016/j.jacc.2025.03.428
- PARTNER 3 Low-Risk
https://www.nejm.org/doi/full/10.1056/NEJMoa2307447
- NOTION at 5 years
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.036606
III The Matter of Pacemakers After
TAVI
- JACC IV Study Badertscher
https://www.jacc.org/doi/10.1016/j.jcin.2025.03.028
- Assessing the quality of reporting of harms in
randomized controlled trials published in high impact
cardiovascular journals
-
IV Mavacamten Looks to Have Specific
Indications
- EXPLORER HCM 10.1016/S0140-6736(20)31792-X External
Link
- VALOR HCM
https://jamanetwork.com/journals/jamacardiology/fullarticle/2809050
- BMS Press Release
https://news.bms.com/news/details/2025/Bristol-Myers-Squibb-Provides-Update-on-Phase-3-ODYSSEY-HCM-Trial/
FINAL THOUGHTS
- PRAGUE 25
https://bmjopen.bmj.com/content/12/6/e056522
You may also like:
The Bob Harrington Show with the Stephen and Suzanne Weiss Dean
of Weill Cornell Medicine, Robert A. Harrington, MD.
https://www.medscape.com/author/bob-harrington
Questions or feedback, please contact news@medscape.net