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This Week in Cardiology

Mar 17, 2023

ACC Recap No. 2: Pacing in HFpEF, Oral PCSK9 inhibitor, PAH, soft thinking on adherence, and so called metabolically healthy obese are discussed by John Mandrola, MD, in this week’s podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

I. Pacing in HFpEF

No Exercise Boost From Pacemaker in HFpEF With Impaired HR Response: RAPID-HF

- Rate-Adaptive Atrial Pacing for Heart Failure With Preserved Ejection FractionThe RAPID-HF Randomized Clinical Trial

- Accelerated Pacing a Possible Strategy for Preserved-EF Heart Failure?

- Could a Breakthrough in Heart Failure With Preserved Ejection Fraction Just Take a Change of Pace? -

- Effect of Personalized Accelerated Pacing on Quality of Life, Physical Activity, and Atrial Fibrillation in Patients With Preclinical and Overt Heart Failure With Preserved Ejection Fraction: The myPACE Randomized Clinical Trial

- Effect of β-Blocker Withdrawal on Functional Capacity in Heart Failure and Preserved Ejection Fraction

II Oral PCSK9i

Oral PCSK9 Inhibitor Shows Encouraging LDL Lowering

- Efficacy and safety of the oral PCSK9 inhibitor MK-0616: a phase 2b randomized controlled trial


'Unheard of' PAH Improvement With Novel Drug: STELLAR

- Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension

IV Medical Adherence

Waiving Co-Pays for CV Meds as Adherence Incentive Doesn't Cut Clinical Risk: ACCESS Trial

- Eliminating Medication Copayments for Low-income Older Adults at High Cardiovascular Risk: A Randomized Controlled Trial

- Medicaid Expansion: Good First Step, but No Panacea for CV Care

- Health Care Access and Management of Cardiovascular Risk Factors Among Working-Age Adults With Low Income by State Medicaid Expansion Status

- Rand Link

- The Oregon Health Insurance Experiment

- Effect of Health Insurance in India: A Randomized Controlled Trial

- Full Coverage for Preventive Medications after Myocardial Infarction

- Effect of Medication Co-payment Vouchers on P2Y12 Inhibitor Use and Major Adverse Cardiovascular Events Among Patients With Myocardial InfarctionThe ARTEMIS Randomized Clinical Trial

- Coronary CT Angiography and 5-Year Risk of Myocardial Infarction

IV Metabolically Healthy Obese

'Metabolically Healthy Obesity' Rising, but Still Uncommon

- Trends in the Prevalence of Metabolically Healthy Obesity Among US Adults, 1999-2018

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The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD.

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