Sep 16, 2022
The safety of very low LDL-C, the win-ratio analytic method, sacubitril/valsartan, SGLT2 inhibitors, and percutaneous left atrial appendage closure are discussed in this week’s podcast.
This podcast is intended for healthcare professionals
only. To read a partial transcript or to comment,
visit:
https://www.medscape.com/twic
I PCSK9I
Evolocumab Benefits Accrue With Longer Follow-up: FOURIER
OLE
https://www.medscape.com/viewarticle/979950
- Evolocumab and Clinical Outcomes in Patients with
Cardiovascular Disease
https://www.nejm.org/doi/full/10.1056/nejmoa1615664
- Long-Term Evolocumab in Patients with Established
Atherosclerotic Cardiovascular Disease
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.061620
II Analytic Methods and Re-Analysis of Old Trials
- PARADISE-MI Results Obscured As Post Hoc Analysis Finds
Flaws
https://www.medscape.com/viewarticle/980776
- Angiotensin Receptor–Neprilysin Inhibition in Acute Myocardial
Infarction
https://www.nejm.org/doi/10.1056/NEJMoa2104508
- Impact of Sacubitril/Valsartan Versus Ramipril on Total Heart
Failure Events in the PARADISE-MI Trial
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.057429
- The Year’s Most Important Study Adds to Uncertainty in
Science
https://www.medscape.com/viewarticle/904286
III SGLT2i Post MI
- Early Signal of Benefit for Empagliflozin in Acute MI:
EMMY
https://www.medscape.com/viewarticle/980180
- Empagliflozin in acute myocardial infarction: the EMMY
trial
https://doi.org/10.1093/eurheartj/ehac494
IV Percutaneous Left Atrial Appendage Closure
- Incidence and Predictors of Early Death in Patients Undergoing
Percutaneous Left Atrial Appendage Closure
https://www.jacc.org/doi/10.1016/j.jacep.2022.06.012
- Cost‐Effectiveness of Left Atrial Appendage Closure for Stroke
Reduction in Atrial Fibrillation: Analysis of Pooled, 5‐Year,
Long‐Term Data
https://www.ahajournals.org/doi/10.1161/JAHA.118.011577
- Baseline Comorbidities And Bleeding Events Of Patients
Undergoing Percutaneous Left Atrial Appendage Occlusion Among
Medicare Beneficiaries
https://www.jacc.org/doi/10.1016/S0735-1097%2822%2901158-5
You may also like:
Medscape editor-in-chief Eric Topol, MD, and master storyteller
and clinician Abraham Verghese, MD, on Medicine and the Machine
https://www.medscape.com/features/public/machine
The Bob Harrington Show with Stanford University Chair of
Medicine, Robert A. Harrington, MD.
https://www.medscape.com/author/bob-harrington
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