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This Week in Cardiology

Apr 28, 2023

Two studies of cardiac device infections, observational studies, RCTs, and our ways of knowing in Medicine are the topics discussed by John Mandrola, MD in this week’s podcast.

This podcast is intended for healthcare professionals only.

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I. Cardiac Device Infection

Mortality Climbs When CIED Infections Are 'Delayed' After Implant

- Association of the Timing and Extent of Cardiac Implantable Electronic Device Infections With Mortality

- Low Utilization of Lead Extraction Among Patients With Infective Endocarditis and Implanted Cardiac Electronic Devices

- Cardiac Implantable Electronic Devices and Infective Endocarditis: A Call to Arms...

II. Can RCTs be Emulated with Real World Evidence?

- Emulation of Randomized Clinical Trials With Nonrandomized Database Analyses

- Randomized Trials vs Real-world Evidence

- Reanalyses of Randomized Clinical Trial Data

III. Multi-Morbidity Effects in Trials

Pivotal CV Trials May Not Apply to Complex Patients

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