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This Week in Cardiology

Mar 29, 2024

Intermittent fasting, anticoagulation decisions, heterogenous treatment effects, frailty in HF, the importance of the ECG, and industry conflicts are the topics John Mandrola, MD, covers this week.

This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit:

I. Intermittent Fasting

No, Intermittent Fasting Won't Kill You

  • NEJM Paper on Time-Restricted Eating
  • JAMA TREAT Clinical Trial

II. Stroke Prevention with OAC

  • Shah Meta analysis of Vitamin K Agonists in AF

III. Heterogenous Treatment Effects in Trials

Pivotal CV Trials May Not Apply to Complex Patients

  • Analysis of 8 Trials of Multimorbidity and Treatment Response

IV. Frailty and HF

  • Circulation Outcomes: Multidomain Frailty and Mode of Death in HF


  • JAMA Cardiology: Revised Definition of LBBB

VI. Industry Payments to Doctors

  • JAMA: Payments to US Physicians by Specialty

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